Viagra vs. sealing–it might help the sealers, too

From ANIMAL PEOPLE, June 2001:

ST. JOHN’S, New-foundland–Seal pelt prices tripled and a two-week extension of the Atlantic Canada seal hunt, originally to have ended on May 15, encouraged sealers to kill two to three times as many infant harp seals in 2001 as in 2000. Just 91,000 seals were landed in 2000. By early May 2001, the toll stood at 186,000.

But even selling pelts for $40 in Canadian money, up from $13, will not leave sealers with more than a marginal profit. A June 15 report by Canadian Institute for Business and the Environment president Gary Gallon, commissioned by the International Fund for Animal Welfare, found that federal and provincial governments have spent $20.5 million [Canadian funds] since 1995 to prop up sealing via 38 different subsidy programs.

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Bite treatment producers prepare for monsoons

From ANIMAL PEOPLE, June 2001:

PUNE, HYDERABAD, CHENNAI– The interfacing politics of snakebite treatment, rabies vaccination, and laboratory animal care in India heated up with the approach of the summer monsoons. In Pune the Haffkine Institute disclosed that it had resumed production of snakebite antivenin on May 30, despite lack of authorization from the Committee for the Purpose of Control and Supervision of Experiments on Animals, which closed the facility on March 26.

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The transgenic dilemma: Body or soul?

From ANIMAL PEOPLE, April 2001:

Are you eating pork when you eat a tomato? Would having fish genes qualify a pig as “not pork”? Is a cow with human genes either more or less holy than a cow without?

In the brave new world of biotech, such questions make careers for lawyers and philosophers–and terrify the faithful. Even as biotech makes food more resistant to viruses, bacteria, mold, and fungi, vegans often find that trans-species
hybridization complicates their effort to avoid all traces of animal products and byproducts. Orthodox Jews, Hindus, Jains, and Muslims may even feel that biotech puts their souls at risk.

The appeal of absolute belief tends to be that it establishes easily understood rules of conduct. The more basic the belief, the simpler the rules: Thou Shalt. Thou Shalt Not. One God. Ten Commandments: no more than can be counted on fingers.

But simple rules require simple definitions. And in transgenic and xenographic science, there are none. That makes the traditional Jewish and Islamic prohibitions on consuming pork and the Hindu proscription against eating beef a series of religious, philosophical, and political battlegrounds. The Jain prohibition on ingesting any living being in any form,  always hard to obey because of the dfficulty of seeing small insects, already became impossible for strict literalists with the discovery of microbes, but the injunctions against pork and beef have endured centuries, withstanding translation into every language and transplantation into every human culture–until now.

Now they are confounded by medical and agricultural practices which have become routine in some parts of the world while still unknown in others. Pigs’ heart valves have been implanted in humans for more than 25 years, for instance, and skin grafts from pigs have been used to help burn patients. Until recently, such techniques often took decades to
perfect. But biotech advances seem now to be accelerating to warp speed the research, development, and testing phases of transgenic and xenographic procedures.

When pigs fly

Just over three years ago, in March 1998, 38-year-old James MacDonald, of West Lafayette, Indiana, received the first
transplant into a human of small intestinal submucosa from a pig, as part of a surgical knee reconstruction. In February 2000 the Food and Drug Administration approved the use of pig small intestinal submucosa as a patching material for almost any sort of soft-tissue wound–even eye injuries and some types of stomach ulcer. Now SIS, as it is called, has been used to treat more than 25,000 human patients, and is well on the way toward even more common use.

A similar product made from a matrix of collagens taken from the livers, stomachs, and urinary bladders of pigs has been used to make replacement larynxes, intestines, and other organs for about 30 dogs whose original organs were removed as part of the study, Purdue University Department of Biomedical Engineering senior researcher Stephen Badlylak disclosed on March 22. This product too is believed to be on the fast track to FDA approval and general use.

In 1998, doctors disclosed experimental use of pig livers to keep human liver transplant candidates alive pending receipt of livers from human donors; transfusions of pig blood into humans; transplants of cells from genetically modified pigs to treat human spinal cord and brain injuries; and injections of fetal pig brain cells into the brains of Parkinson’s Disease patients.

Experimental use of fetal pig tissue to treat diabetes began in mid-2000, under direction of Diacrin Inc. researcher Jonathan Dinsmore. If that treatment works, it could improve the quality of life for 1.5 million Americans, plus millions more people abroad. At about the same time in mid-2000, researchers in Japan, Scotland, Virginia, and Wisconsin separately announced the births of cloned pigs, a first step toward mass production of pigs genetically modified to supply replacement organs for people. Reports indicate that any or all of these procedures could soon follow SIS into frequent application.

The market for human use of genetically modified pig parts is believed to be so potentially lucrative that the Hormel and Smithfield pork-packing empires have invested millions of dollars in related research, with partners including the Mayo Clinic, Baxter Healthcare, and ProLinia Inc. The pork barons are hoping to catch up to the Imutran, Infigen, and Geron Bio-Med research empires, whose scientists are believed to be the leaders in research and development.

People who eat pork are not expected to have ethical qualms about accepting transplants from pigs–and that includes most of the population in the most affluent parts of the world. For those who object to pig parts, alternatives may eventually be developed, grown in other species. Researchers, ethicists, and investors tend to believe that anyone who eats meat will readily accept transplants and other products modified through the use of animal genes, as soon
as they are proven safe.

PERV throws curve

Animal welfare concerns are not considered to be much of an impediment to transgenic biotech either–because most of the source genetic material can be taken from animals who were raised to be butchered anyway; because animals raised specifically to provide organs for transplant must be kept in healthier conditions than meat production facilities afford; and because the advent of genetic modification enables researchers to use far fewer animals in each new
product safety test. The effect of procedures or substances on human organs may now be studied by inserting human genes into the bodies of test animals to give their organs human properties.

Conventional wisdom in the biotech field is that genetic research is far more compatible with animal welfare than the search for drugs and surgical treatments. In August 2000, however, concern about the liabilities associated with pig endogenous retroviruses (PERV) caused the Roslin Institute of Scotland and Geron Bio-Med of California to drop out of the race to produce replacement human organ in pigs.

Although PERV does no harm to pigs, and so far does not appear to infect people, British virologist Robin A. Weiss proved in 1997 that cross-species infection can occur via test tube. Since PERV invades cells in much the same manner as HIV, integrating itself into the genetic program of the host, there are scary implications should people ever become vulnerable to a PERV strain.The PERV problem seemed to be solved in December 1999, when Bio-Transplant Inc. researcher Clive Patience announced that his team had bred a genetically modified pig which does not carry PERV.

The London Sunday Times reported in August 2000 that, “The use of pig organs for transplant to humans is poised to win governmental approval.” But the BioTransplant claim has apparently not yet been independently confirmed. And even as Sunday Times reporters Jonathan Leake and Lois Rogers wrote, the British Natural Environment Research Council revealed that Imperial College researchers Michael Tristem and Joanne Martin had found evidence that some pig retroviruses jump species barriers in the wild.

“When viruses jump species, they usually acquire pathogenic properties,” Tristem told London Observer science editor Robin McKie.The Boston-based Society for Heart and Lung Transplantation reinforced the British findings with a warning about PERV in December 2000. In February 2001 the third annual report of the United Kingdom Xenotransplant-ation Interim Regulatory Authority cautioned that due to PERV and unsolved tissue rejection problems, “The likelihood of whole-organ xenotransplantation being available within a worthwhile time frame may recede.”

Commented Interim Regulatory Authority member and heart transplant surgeon John Dark, of Newcastle, “Xenotrans-plantation is the future of transplants–and it always will be.” But even if people never receive replacement organs
cultivated in pigs, surgical use of other pig parts is likely to keep growing.

Hybrid cowboys?
Applications of biotech involving cattle to human health care were relatively slow to emerge. The emphasis of genetic research with cattle has mainly been on producing more lucrative dairy and beef breeds. Ethical discussion remained subdued until October 1998, when Vandana Shiva of the New Delhi-based Research Foundation for Science, Technology, and Ecology warned India that the Roslin Institute had applied for a patent on the genetic properties of the vechur cow. The vechur is a rare Indian breed, found mainly in Tamil Nadu and Kerala states.

Shiva urged the Indian government to assert a claim to the genetic properties of all native Indian animals and plants.
Other commentators soon linked the scientific, legal, and economic issues that Shiva raised to ethical concerns involving the treatment of the “Mothers of India.” Especially offensive to many Hindus would be the use of genes
from Indian cattle to make cow slaughter more profitable.

On the far side of the world, Advanced Cell Technology chief executive Michael West, of Boston, was successfully melding human DNA with a cow’s ova to produce a hybrid cell of potential utility in growing organs in cows which will be compatible with human bodies. Concern that the procedure might produce a hybrid fetus or lead to cloning humans was so prominent in news coverage during November 1998 that then-U.S. Presi-dent Bill Clinton sought the advice of the National Bioethics Advisory Commission. A hearing was held in Miami, a non-committal report was issued, and the work proceeded.
Unmollified, prominent voices from the Christian right have persistently demanded that the National Bioethics Advisory Commission be dismantled–which would actually diminish public oversight of genetic research.

Low average

Michael West, meanwhile, claimed in April 2000 that while sheep cloned by the Roslin Institute have shown symptoms of premature aging, his cloned cattle seem to be free of the problem. That might make them better candidates than pigs for use in growing replacement organs. But West had produced a calf fetus in only one of 271 attempts. The major anticipated application of biotech to cattle for human medical benefit would be the use of cows as living bioreactors,
who would be genetically modified to secrete human proteins used in drugs.

As this essentially involves only making medicines from milk, a classic Vedic procedure, there is no Hindu resistance to it in concept. Nor is there evident opposition in principle within the U.S. except from opponents of any genetic modification. Neighbors concerned mainly about manure and traffic and only secondarily anxious about biotech have put up the only visible resistance so far to plans by the Dutch pharmaceutical firm Pharming Group N.V. to build $37 million worth of facilities to produce drugs from genetically modified cow’s milk at Craig, Virginia, and at Virginia Tech University.

The Pharming Group project was first announced in early 1999. In August 1999, Agresearch Inc. outlined a similar project that it wanted to start near Wellington, New Zealand, on land leased from the Maori tribe. The Agresearch proposal met heavy resistance. Two members of the Ngati Wairere subtribal council delegation supported Agresearch;
five were opposed.

“It’s a mixing of whakapapa between species which is culturally inappropriate,” explained Agresearch foe Jacqui Amohanga. But the Agresearch project went ahead, under former Roslin Institute researcher David Wells. The goal is to use milk to produce human myelin basic protein, used to treat multiple sclerosis.

Use of actual parts from cattle in human medicine has distantly paralleled the use of pig parts. The first use in the U.S.
of a bovine valve in a human heart, for example, occurred in May 1999, following a procedure previously used in Europe. A valve from a bovine neck was used instead of a pig’s heart valve because a pig’s heart value would have been too large for the patient, a 13-month-old boy who was born with a severe congenital heart defect. He will have to receive the larger valve later, at about age 10.

The biggest subsequent development in cow-to-human xenography, announced on February 22, 2001 by PPL Therapeutics, was a technique for altering so-called stem cells from cow’s skin to produce heart muscle. Commented Donald Bruce, director of the Church of Scotland’s Society, Religion, and Technology Project, “This is an encouraging
breakthrough in the search for replacement cells to treat serious diseases without the need to use human embryos. It is obviously still too early to say that this is the solution we have been looking for, but it is certainly a step in the right direction.”

Tossing tomatoes

Researchers and the medical products industry would mostly prefer that the public continue to believe that pigs are pigs if they look like pigs; cows are cows if they moo and give milk; pig and cattle products are taboo for Jews, Muslims, and Hindus only if ingested as food; and people can otherwise do as they wish with livestock.

Fundamentalists are not so certain. Few fundamentalist leaders, of any religion, have ever fully trusted science. The
scientific method requires questioning certainties of the faith, while the findings of science tend to push the realm of God–the unknown–ever farther from daily human existence. Science shrinks the authority and prestige of priests. Science upsets the social order.

Science means trouble, in short, and when it comes coupled with putting parts or genetic information from one species into another, it also takes the form of an ancient dirty trick: causing thr religious to transgress a taboo unawares. It is said that the Buddha, who ate no meat, died when someone slipped pork into his begging bowl–a story which may least concern Buddhists, many of whom eat pork.

Some of the bloodiest riots in the history of India resulted from rumors that British troops had given Moslem and Hindu recruits weapons greased with lard and beef tallow. As recently as January 23, 1999, alleged Hanuman worshippers burned to death Australian missionary Graham Staines, 58, and his sons, ages 6 and 10, over evidently completely unproven rumors that they had tricked Hindus into eating beef, thereby “forcing” conversion to Christianity.

So what happens when a Jew, Moslem, or Hindu receives a transgenic or xenographic medical treatment? Or eats a genetically modified vegetable? Is such an act sinful? The question may have arisen first in Israel, where surgeons
began implanting pig heart valves in humans about 20 years ago, soon after the procedure was introduced in the U.S. and Britain. It came up again in April 1998, in discussion of a proposed pig-to-human heart transplant which would not have been done in Britain, at the time, because of concern about PERV.

“We as Jews are not supposed to eat the meat of a pig, but there is no reason not to use it to save a human life,” said Shear Yashu Cohen, chief rabbi of Haifa and of the Ariel Institute, a rabbinical training center. Universiti Sains Malaysia theologian Wan Salim Wan Mohd Nor, Ph.D., and associate professor of medicine Mohd Nizam Isa, M.D., likewise argued for tolerance at an April 2000 symposium. “When there is no other option, it should be all right to use pig organs,” Nor said, putting the obligation to protect human life ahead of dietary law.

Added Isa, “We cannot afford to close an eye to technology. To debate the issue in relation to moral, ethical, religious, and economic implications, we must first understand what the technology is all about.” But in June 2000, Muslim genetic engineering opponent Chamnong Buanien, of Thailand, invoked the alleged use of a gene from pigs to keep tomatoes fresh as a hoped-for ultimate weapon against the introduction of genetically modified crops in the
southern provinces of Satun and Songkhla, where most Thai Muslims live.

Epidemic of faith

From ANIMAL PEOPLE, April 2001:

LONDON–A combination of misplaced faiths brought the world the widest outbreak of hoof-and-mouth disease ever– and the most virulent known strain:

* Millions of Islamic faithful mistakenly believe that the Koran commands them to kill a hooved animal at the yearly Feast of Atonement, and give two-thirds of the meat to the poor.

* Millions of British residents mistakenly believed–until late February 2001–that the English Channel, having protected them against Napoleon, Hitler, and canine rabies, protects them as well against other invaders and diseases.

* Millions of Europeans mistakenly believed back in 1992 that abandoning livestock vaccination against hoof-and-mouth disease would reduce meat prices. Therefore, under the Single Europe Act, the European Union forced eight member nations to repeal as purported artificial trade barriers their national laws requiring that hooved
animals be vaccinated.

Instead, the entire EU adopted the British, American, and Japanese requirement that infected and exposed herds must be killed, on the theory that the highly contagious and easily transported hoof-and-mouth virus could be totally eradicated. Vaccinated animals are considered “exposed,” because the vaccination causes them to produce false positive results in standard testing, and– whether infected or not–vaccinated animals can still be immune carriers.

Now struggling to meet the EU standard, English and Scots officials had by March 28 condemned 719,000 animals–far more than the 480,000 who were killed in the 1967-68 hoof-and-mouth episode that had been Britain’s worst. Incomplete species totals included 420,519 sheep, 118,627 cattle, 46,021 pigs, and 261 goats.Just 728 animals were found to be infected within the first month of the outbreak arriving in Britain, but 441,640 animals had already been killed.

Epidemiologists commissioned by the British government forecast on March 23 that more than 4,400 animals would eventually be infected, twice as many as in 1967-68, without the “immediate slaughter of all susceptible species around infected farms.” British authorities are still traumatized by the ongoing global blame-throwing over their failure to contain bovine spongiform encephalopathy. Better known as “mad cow disease,” BSE emerged circa 1980, and in 1996 was found to have jumped into humans as the brain-destroying new-variant Creutzfeldt-Jakob Disease. Ensuing trade bans devastated the British livestock export industry, once Europe’s largest.

Politicians and public officials who took a decade to respond decisively to BSE lost no time implementing whole-herd slaughters in response to hoof-and-mouth. Indeed, some initiated killing animals so enthusiastically that they created a whole new health problem.

Napalm

Concerned that decomposition in the soil might cause water pollution, British government veterinarians initially tried to burn the fast-accumulating corpses. Rehearsing for just such a disaster, government purchasing agents solicited bids on firewood and coal to stoke bonfires of dead livestock shortly before Christmas. But burning the animals proved too slow, at three days per pyre, while a 10-day backlog of bodies festered, and merely piling the remains up with fuel gave badgers, foxes, feral pigs, birds, insects, and other carrion-eaters ample time to spread the hoof-and-mouth virus farther.

Agriculture minister Jim Scudamore delayed action on National Pig Association and British Wild Boar Association recommendations that the feral pigs and boars be killed–perhaps because no one, anywhere, has ever succeeded in eradicating feral swine from a land mass larger than the Catalina Islands, off southern California. Several advisors reportedly told Scudamore that it probably could not be done with the resources available.

Soldiers finally excavated pits to hold up to half a million dead animals at the abandoned Great Orton military airfield in northern England, and Scotland called out the Highlanders 1st Battalion to dig holes for a quarter million more at Brickshaw Forest, near Locherbie. Almost 100,000 bodies remained unburied as ANIMAL PEOPLE went to press, and the Agriculture Ministry was considering a suggestion from Nevada Department of Agriculture expert Ron Anderson that they should incinerate them with napalm. Anderson said napalm had served him well against an August 2000 outbreak of anthrax.

The London Zoo and the 61-member Federation of Zoos unsuccessfully petitioned the Ministry of Agriculture for exemptions from mandatory slaughter of hooved animals, and asked to be allowed to vaccinate their rare and endangered species instead. At risk were elephants, bison, rhinos, hippos, okapi, antelope, camels, deer, and 48 of the last 59 Northumber-land cattle, whose herd has lived within the same 300-acre walled enclosure at Chillingham since
approximately 1300. Doomed were the almost equally rare Herdwick sheep of Lake District National Park, after the hoof-and-mouth virus was apparently carried 20 miles on the wind to infect cattle pastured nearby.

Misconceived

“There are grounds for arguing that the slaughter policy is misconceived,” opined BBC News environment correspondent Alex Kirby as early as February 25. “It is not strictly necessary, as the disease poses no real risk to human health. At most, it can lead to a mild infection, and it is not invariably fatal to the animals. In adult cattle only a small minority succumbs, though the death rate can be much higher in younger animals and pigs.” The major effect of hoof-and-mouth, Kirby explained, is that afflicted animals suffer weight loss, producing less meat and milk.

“But whether that would leave farmers worse off than they are already is debatable,” Kirby said. “The last hoof-and-mouth outbreak in the U.K. was in 1981, which leads the government to argue that slaughtering has worked. But it is at least as logical to say that the U.K. has for 20 years been lucky. The uncomfortable truth is that the day the U.K. is declared free of hoof-and-mouth again, the risk of another outbreak will remain just as high.”

“Once the virus is here,” Kirby continued, “modern farming as good as rolls out the red carpet to greet it. Animals kept in close confinement, reared in close quarters, will inevitably infect one another very quickly.”

Commented virologist Fred Brown, of the USDA Plum Island Animal Disease Center, located in Long Island Sound, “It’s quite clear that if you stop vaccinating, you’re vulnerable.” Brown explained to Los Angeles Times staff writer Emily Green that since 1997 a new test has been developed, but not widely deployed, which can distinguish the false positive result caused by vaccination from the actual disease. Britain and other nations, as well as consumers’ groups, opposed mandatory vaccination because of the anticipated cost: more than $900 million per year in Britain alone, estimated British agriculture minister Nick Brown.

But insuring British farmers against losses comparable to those resulting from the hoof-and-mouth outbreak would cost $800 million. Currently, only 10% have insurance against disease outbreaks, in part because the cull of 4.7 million cattle in the thus-far futile effort to eradicate “mad cow disease” sent the premiums soaring. $900 million is, coincidentally, approximately the same amount as has been budgeted by the European Union to combat BSE. About 300 million animals within the EU might be potentially vulnerable to hoof-and-mouth.

Rethink?

“In light of the questions now being asked in Britain and the rest of Europe about whether non-vaccination strategies are really worth the occasional massive slip-up,” commented New Scientist European correspondent Debora MacKenzie in a comparison of notes with ANIMAL PEOPLE, “I am trying to re-examine such policies. While I
understand the reasons for them, I wonder if both the risks and the technology have not moved on, and made it time for a re-think.

“The whole system rests on the possibility of keeping pathogens out of an area post-eradication and post-vaccination. But it seems to me the risk of introducing pathogens has increased substantially recently with increased global trade and travel, while the impact of introduction has also increased along with livestock density. Has the cost-benefit ratio favouring the maintenance of large numbers of un-immunised animals perhaps shifted against non-vaccination as a result of this?

“Marker vaccines,” which can be distinguished from the actual illness, “and molecular surveillance,” permitting early
discovery of hoof-and-mouth, “may allow vaccinating and detecting the pathogen well enough,” MacKenzie suggested, “to prevent infection without risking an epidemic.”

The EU on March 24 authorized the Netherlands to make limited use of vaccination, if the Dutch government cannot kill animals fast enough to halt the spread of hoof-and-mouth. But disposing of remains is expected to be the biggest problem for the Dutch, whose low land and high water table make burial out of the question. Also lacking safe places to maintain long-burning bonfires, the Nether-lands may just have to use napalm.

BSE confusion

The cost of the epidemic was evident even in the U.S., where suspected hoof-and-mouth outbreaks have recently occurred only in Idaho. Hoof-and-mouth was officially eradicated from the U.S. in 1929 and from all of North America by 1952, Associated Press farm writer Philip Brasher reported. The U.S. has prohibited imports of hooved animals from any nation with hoof-and-mouth or which vaccinates hooved animals against hoof-and-mouth since 1930.

But Agriculture Secretary Ann Veneman complained to Brasher on March 27 that the meat industry is suffering nonetheless, in part because American consumers, she said, are confusing hoof-and-mouth with BSE. BSE, in the mutated form of nv-CJD, has killed at least 86 people–but has never been found within U.S. cattle. Veneman spoke, however, less than a week after a new report by the Food and Drug Administ-ration found that nearly 700 of the
2,500-odd U.S. rendering plants and animal feed meals have inadequate controls to keep mammalian meat and bone meal out of food meant for cattle, sheep, goats, deer, and elk –the species believed vulnerable to getting BSE as result of eating the remains of sheep infected by scrapie. Maybe Americans were not so confused after all.

Renewed BSE scares in Europe combined with concern about hoof-and-mouth to bring a 10% sales decline at European franchises of McDonald’s restaurants –“no small amount,” reported Daryl Lindsey of Salon.com/news, “considering that the company derives as much as 36% of its operating income from the continent.”Lindsey said that McDonald’s was being forced to “fast-track the mainstreaming” of vegetarian products test-marketed in New York,
Amsterdam, and India.

Pan-Asia

The role of faith in bringing on the animal massacres might have come to fore when 5,000 sheep and cattle belonging to farmer John Fisher were burned over a week’s time at Arthuret Knowes. On March 16, Matthew Engel of The Guardian watched the pyre from a sign commemorating the Battle of Aedderyd in 573. “On this spot,” Engel wrote, “the pagans of Strathclyde were slaughtered by the Christians of Cumbria. Though the pagan king Gwenddolau had Merlin [of Arthurian legend] to encourage him, 80,000 humans were killed.” Their remains too were burned.

But religions and ancient beliefs other than Christianity and nature-worship were most involved in spreading hoof-and-mouth. The pan-Asia hoof-and-mouth strain responsible for the current global epidemic already afflicted hooved animals in at least 25 nations before it hit Britain. Following the same trade routes that the world’s major religions did long ago, the pan-Asia strain may have come south at some point from Pakistan, Kazakhstan, and Georgia, but was first identified in northern India in 1990, according to epidemiologist Nick J. Knowles, of the Institute for Animal Health at Pirbright Laboratory in England.

In succession the pan-Asia strain infected the Hindu world, the Buddhist world, and now the Judeo-Christian/Islamic world. “From India the pan-Asia strain spread east and west: to Nepal in 1993-1994, Bhutan in 1998, and Tibet and Hainan province, China, by 1999,” reported London Times health editor Nigel Hawkes on the morning after the Feast of Atone-ment. “It reached Kinmen Island, between Taiwan and the Chinese mainland. Before anyone realized it was there,” Hawkes continued, “cattle had been moved to Taiwan, carrying the infection with them. The strain has also
hit Mongolia, Burma, Vietnam, Cambodia, Thai-land, Malaysia, Laos, the Philip-pines, Korea,” which had been free of
hoof-and-mouth since 1934, “and Japan,” free of hoof-and-mouth since 1908.

Seventeen outbreaks afflicted 2,152 pigs in Hong Kong, killing 464, during the last four months of 2000, acknowledged
Leslie Sims, assistant director of the Hong Kong Agriculture, Fisheries, and Conservation Department. Waste from an Asian freighter, fed to pigs on a farm near Durban, South Africa, took the pan-Asian strain of hoof-and-mouth on to other African nations. Durban is a major port of call for freighters in the live animal export trade–and an alleged hub of accidental hoof-and-mouth exports. A shipment of 24 giraffes and three rhinos sent from Durban to Spanish exhibition facilities on October 5, 2000, was refused and returned to Durban after 40 days at sea from fear that they might
have hoof-and-mouth. Two of the giraffes died during the journey.

National SPCA of South Africa senior inspector Morgane James warned again of the disease risk inherent in shipping live animals as recently as February 27, after discovering 34 sick animals among a cargo of 1,500 goats and 10,000 sheep who were en route via Durban from Namibia to Saudi Arabia aboard the livestock carrier Holstein Express. About 15 animals had already died, James said; 10 were euthanized aboard the ship, and two dozen were treated.
Namibian environment and tourism minister Tangeni Erkana on March 16 banned live exports of native wildlife, as a conservation measure, but the livestock traffic was not affected.

Mecca

Meanwhile, Hawkes of the London Times explained, based on Knowles’ findings, hoof-and-mouth “spread to Saudi Arabia, probably through the trade in live sheep and goats, and then into Turkey, Greece, and Bulgaria” by 1996. It went on to afflict Iran, Iraq, Syria, Israel, Lebanon, Jordan, and the kingdoms of the Arabian Peninsula–possibly carried by Muslim pilgrims returning from Mecca, who might have transported the hardy virus unaware of having ever
encountered it.

Saudi Interior Minister Prince Naif formed a special commission to fight hoof-and-mouth in mid-March 2001, amid new
outbreaks in and around the cities of Jeddah, Yanbu, and Kamis Mush-yat, and Dubai in the United Arab Emirates.
Other outbreaks appearing within 10 days of the Feast of Atonement hit Iran and Sri Lanka. By then, the disease could have come from almost any direction.

On February 22, 11 days before the Feast of Atonement, hoof-and-mouth apparently entered the Netherlands with 230 calves brought from Ireland by way of Mayenne, France. In Mayenne they were in proximity to the sheep who suffered the first French outbreak of pan-Asian hoof-and-mouth. The strain then broke out on all three Dutch farms which received some of the infected calves. More than 20,000 animals including 662 farmed deer were killed to try to stop the Dutch outbreak. Year-round, the Netherlands imports about 25% of all the livestock shipped from Britain, then re-exports most of them.

At least some of the animals imported in late February are believed to have been imported for resale to the Halal butchers serving the sizeable Dutch Muslim minority. The Netherlands ruled much of largely Muslim Indonesia for nearly 300 years, and did not surrender its last holding, the island of Irian Jawa, until 1962. Sheep imported from Britain during the same time frame are believed to have taken hoof-and-mouth to Germany, where Islamic immigrants from Turkey form the largest ethnic minority. The exact means by which the pan-Asian strain travels are still unknown. Saudi experts, frustrated by repeated failures of quarantine, think it might be carried by dirty shoes. Pigs were the
suspected major carriers in southeast Asia and Britain, but are rarely kept in the Islamic world because Muslims do not eat pork.

Abraham

Islamic health authorities anticipated that the public animal massacres held on March 5 to mark the annual Feast of Atonement might bring epidemics. Like the feast itself, marking the end of the Islamic equivalent of Lent and the reputed day on which Abraham sacrificed a ram allegedly sent by God instead of his son Isaac, disease outbreaks linked to the killing are an annual event.

A thousand years ago Islamic physicians were the world leaders in medical knowledge and research. They knew even then that epidemics can be spread by pilgrimages, mass movements of stressed animal herds, and the rotting remains of animals left in streets. For centuries, Islamic medical experts have tried with limited success to temper the zeal of the faithful for killing which is not demanded anywhere in the Koran, yet is almost universally believed to be a religious duty.
“My grandfather and grandmother always used to say it was important to let blood flow inside the house at least once a year,” Damascus housewife Ilham Abdi, 41, explained to New York Times correspondent Neil Mac-Farquhar. “It’s a blessing for the family. It keeps away sickness and the evil eye,” Abdi insisted. But if anything associated with the killing protected her household, it was the vigorous post-slaughter clean-up. MacFarquhar also noted fly infestations following the disposal of offal in the streets, and the incidence of self-inflicted accidental knife wounds among men attempting to do their own Halal slaughtering. In 2001, as always in recent years, Islamic health experts struggled to head off disaster.

Responding to apparently false reports of “mad cow disease” appearing in Thailand, Malaysia on February 14 banned the import of Thai cattle. Fighting anthrax outbreaks since January, agriculture officials in West Java, Indonesia, distributed 130,000 free vaccinations to owners of cattle and goats. In Istanbul and Ankara, Turkey, news media urged the faithful to heed governmental pleas to do their slaughtering at officially approved sites, where hygienic conditions could be monitored.

In Britain, Halal Food Authority president Masood Khawaja urged Muslims to “send equivalent money that would be spent on the sacrifice to underprivileged countries.”

Not “sacrifice”

The term “sacrifice” is actually a misnomer. Animal sacrifice is no more a part of Islam than it is of Judaism or
Christianity. The Feast of Atonement is a meal held in conjunction with a religious occasion, like the Seder at Passover and Easter Sunday dinners, but it is not a religious rite in itself. Further, although the killing is customarily done as a
public display of appreciation for good fortune, it is not actually an event that many people choose to watch.

Public officials in Tereng-ganu, Indonesia, this year misunderstood the reason for the killing being done in public, and
tried to promote the Halal-style massacre of 1,000 cattle as a tourist attraction, using the motto “Tour Kuala Terengganu and perform your religious obligation.” They cancelled the event on March 1, after selling just 70 tickets.

In Afghanistan, the Taliban mullah Mohammed Omar, 40, on March 16 ordered a second round of slaughter, reportedly to atone for the slowness with which Taliban troops destroyed two gigantic statues of Buddha carved into cliffs in the Bamiyan Pass during the 3rd and 5th centuries A.D. Taliban spokesperson Sayed Rahmatullah Hashimi, 24, told
Barbara Crossette of The New York Times that the statues were destroyed as false idols because a delegation from the United Nations Educational, Scientific, and Cul-tural Organization offered funds to protect and maintain the statues, but refused to lift economic sanctions imposed against the Taliban because it has sheltered international terrorist suspect Osama bin Laden.

The Taliban had asked for food aid, amid winter famine. The 100 cattle who were killed in the Bamiyan atonement exercise were butchered and distributed to hungry Afghanis, but did not go far. Muslims are asked to help the poor as a central feature of the Feast of Atonement. As the poor rarely could afford meat in ancient times, and winter feed stocks often ran thin before spring, herding peoples came to mark the occasion by culling their camels, sheep, goats, or cattle, and giving the remains to the starving.

Long after the ancient practices lost their original meaning, they continue. And, though Masood Khawaja only asked Muslims to do exactly what Mohammed originally wanted–to help the poor, not kill animals per se–a shortage of Halal-slaughtered meat in British stores and a shortage of animals to buy for custom slaughter is suspected of contributing to the illicit traffic in uninspected livestock which is believed to have had a major role in distributing the pan-Asia strain of hoof-and-mouth, as the current epidemic is called, around the world.

Reservoirs

There are three semi-permanent reservoirs of hoof-and-mouth disease, all in areas associated with clandestine cattle
trafficking: South America, eastern Africa, and India. University of Manchester veterinarian and historian Abigail Wood traces the first British outbreak to cattle brought from Argentina in 1839.  British troops may then have taken hoof-and-mouth to Kenya and India.

“Reluctant to undermine a renaissance of Argentine steak on world markets, the Argentine government hid an outbreak of hoof-and-mouth for months,” Washing-on Post correspondent Anthony Faiola disclosed on March 17. Rancher Enrique Klein told Faoila that the outbreak appeared in the Santa Fe region, 170 miles northwest of
Buenos Aires, in early January. Klein said he had 300 cases in his own herd alone. He reported the outbreak promptly, he said, and the National Sanitary and Agricultural Quality Control Service responded with aggressive vaccination, but did not disclose the outbreak to world health monitors.

By March 22, Argentina was fighting as many as 53 hoof-and-mouth outbreaks in four provinces. Relying on vaccination, and knowing that beef export markets had been lost for years to come, Argentine officials said they would not resort to mass slaughter. But if slaughter brokers couldn’t ship Argentine cattle to Europe, they speculated, perhaps they could ship horses. Coinciding with slumping beef sales, European buyers nearly doubled the price paid for Canadian horseflesh between mid-January and mid-March, Claude Bouvry of Bouvry Exports told Vancouver-based
author Nich-olas Read. Reputedly selling mainly foals born to mares used on pregnant mare’s urine production lines, in connection with making the Wyeth-Ayerst estrogen supplement Pre-marin, Bouvry owns three slaughterhouses in Quebec and Alberta.

The high prices apparently inspired one Argentinian broker to batch 700 horses in Buenos Aires and 200 more in Uruguay, obtained on the pretext of needing carriage horses and riding horses in Italy. They were to be shipped aboard the Holstein Express (the same transporter that carried sick animals from Namibia en route to Saudi Arabia but was intercepted by the National SPCA of South Africa), and were to be landed at La Spezzia, near a horse slaughtering plant which is reputedly among the major sources in the world for ponyskin.

Martha Gutierrez of the Buenos Aires-based Asociacion para la Defensa de los Derechos del Animal was at deadline trying to stop the shipment, but found that international animal protection charities including Compassion In World Farming and the World Society for the Protection of Animals were not very helpful. “The export of the horses is legal, as the buyer says they are going for riding and not for slaughter,” WSPA representative John Walsh told Gutierrez. “Therefore, all we can do is prove in Italy that they will actually be slaughtered.”

Masai

The Masai, of Kenya, herd a rugged breed of cattle with strong resistance to hoof-and-mouth –which the Masai call by the same word they use for the common cold, according to Associated Press correspondent Alexandra Zavis. The Masai, whose herds have been diminished by drought over the past year, are “deeply disturbed by the news that hundreds of thousands of livestock have been killed in Britain to stamp out hoof-and-mouth,” Zavis wrote in a March 23
feature.

“Tribal tradition holds that these herders are the true custodians of all the world’s cows,” Zavis continued, “and the notion of a mass slaughter of otherwise healthy animals is not only horrifying in theory; they take it very personally. ‘If the European people were here in Africa, we could have raided them for this,’ Nicholas Tanyai said angrily,” at a cattle sale in Susua, 50 miles northwest of Nairobi. “‘Just bring those animals that you are killing, and we will buy them.'” Masai cattle enter global commerce mainly when rustled by Somalian militias. That brings the cattle–or their meat–into
proximity with smugglers and arms traders, just a short sail from much of the Middle East.

Toll booths

Masai cattle are only a minor part of the livestock traffic associated with the Feast of Atonement. Indian cattle, on the other hand, often laundered through Bangladesh, are probably the largest illegally trafficked portion. “Under the Cattle Preservation Act, it is illegal to transport cattle across state borders for slaughter,” explained Indian minister for social justice and empowerment Maneka Gandhi. in a recent guest essay for The Times of India. “Cow transportation is
permissible only for draft use or for milking. Since Kerala and West Bengal are the only states where cow slaughter is not banned, it is intriguing that 100% of the cattle transported by train from Punjab, Haryana, and Rajasthan are taken toward West Bengal. Does West Bengal alone have a scarcity of milk cows? Clearly, the movement of cattle toward West Bengal is not for the ostensible purpose of milking, but is rather to feed the smuggling of cattle to Bangladesh,” just across a long open border.

“Statistics clearly indicate that Bangladesh’s leather and beef trade cannot be supported by the nation’s official cattle
population. So where do the cows come from? The railways,” which do most of the long-distance hauling, “are loathe to prohibit transportation of cattle,” Mrs. Gandhi charged. “When the cattle are unloaded at Howrah,” the even poorer
and more chaotic across-the-river twin city to Calcutta, “the dead cows are sold to the leather traders,” Mrs. Gandhi added. “The live ones, if they can walk, are taken to Bangladesh. The West Bengal government refuses to recognize this smuggling. The Bangladesh government taxes it. There are toll booths where every cow smuggler has to pay.”

Railway Traffic board member Shanti Narain professed shock at Mrs. Gandhi’s interference with the timely and profitable running of the trains. “This is giving a bad name to the entire government,” Narain said.

“The world-famous Hari-har Kshetra cattle fair at Sonepur has turned into a mammoth market for smugglers along the Indo-Bangladesh border,” Times of India correspondent Rajesh K. Thakur charged on November 15, 2000. Thakur claimed that of 667 buffaloes sold during the first five days of the fair, 300 “have allegedly been smuggled to 14 different slaughterhouses situated along the border,” among 65 slaughterhouses in the region.

As Thakur’s accusations reverberated, representatives of the Visakha SPCA and the Department of Animal Husbandry and Transport on December 4 seized 122 cattle from six trucks which were allegedly taking them from Srikakulam village, north of Viskhapatnam, to Kerala for slaughter, by way of Hyderabad. Although Kerala is diametrically opposite West Bengal, on the far side of India, the meat from the cattle would probably also have been exported to the
Middle East– in this case, over the Arabian Sea.

The case was significant to documenting the spread of hoof-and-mouth because the seized animals had it. They had either become infected at Srikakulam or aboard the smuggling vehicles. Either way, the vehicles were held just long enough for the drivers to be fined the equivalent of $2.17 apiece. More cattle could have been loaded–and inflected–within hours. And if the smugglers didn’t care to take the same route twice, instead of heading south to Kerala they could as easily put the cattle aboard a northbound train to Howrah. The journeys would be of about equal distance.

Members of People for Animals, founded by Mrs. Gandhi in 1984, intercepted three trains en route to Howrah with cattle during the last 10 days of 2000–two at Ghaziabad and one at Agra. The Agra train was finally stopped after pulling away from five previous stations when a growing mob, chasing the train from station to station, surged across the track at Yamuna bridge station and, led by Agra SPCA founder Krishana Balla, sat on the rails to keep the engineer from leaving. Agra police arrested 128 members of the train crew.

Together, the raids apprehended nearly 3,000 cattle, wrote Manjari Mishra of the Times of India. They routinely found as many as 40 cows and calves packed into cars meant to carry no more than 12. Both Agra and Ghaziabad are much closer to Haryana and Punjab, the region where the pan-Asian strain of hoof-and-mouth was first detected a decade ago, than they are to Howrah. Moreover, hoof-and-mouth is still there, occurring “almost every year,” Punjab Agriculture University pro-vice chancellor K.S. Aulakh told the Press Trust of India.

Trying to contain the most recent outbreak, nine mobile veterinary teams on March 23 began vaccinating cattle in parts of Rajasthan state adjoining Haryana.

Pointing fingers

“Illegal sales of livestock are a worldwide problem,” commented Colorado State University microbiologist Charles H.
Calisher on ProMED, the online bulletin board of the International Society for Infectious Diseases. “Hypocritical functionaries who look the other way when cattle are slaughtered [illegally] or are moved from their country to another country by train, in broad daylight, are known to operate with impunity in the name of national sovereignty. So, disgusting traditions continue without hope for abatement, and maintenance of ‘markets’ are the sine qua non of the industry and of politics.”

The pan-Asia strain is now spreading as rapidly through the Christian world as it did through the Hindu, Buddhist, and Islamic worlds, with greater velocity but often through the same combination of bureaucratic ineptitude, criminality, and finger-pointing in the wrong direction as facilitates the illegal cattle traffic in India. Hoof-and-mouth was officially recognized in Ireland, for example, on March 21, a full month after Irish calves inflected France and the Netherlands.
Irish authorities blamed cattle smugglers, practitioners of an ancient pastime which reputedly supports some units of the outlawed Irish Republican Army.

About 40,000 animals were to be killed on the Cooley Peninsula, in an effort to keep the illness from spreading, but
scarcely anyone seemed optimistic that the killing would succeed. The Dublin stock exchange dropped 5% within one day of the first confirmation that hoof-and-mouth had hit.

French prime minister Lionel Jospin meanwhile blamed an alleged sheep smuggler–by name– in commenting on the discovery of hoof-and-mouth in the Mayenne region of northeastern France. Jospin was then embarrassed when Mayenne prosecutor Philippe Warin told media that there were no grounds for accusing the man, a longtime successful importer of sheep from Britain.

Animal obituaries

From ANIMAL PEOPLE, March 2001:
King Institute mule #291, renamed Tarun in his final days by People For Animals rescuers Prema Veeraraghavan and Shiranee Pereira, died on January 25, soon after Indian minister of state for empowerment and social justice Maneka Gandhi visited the King Institute to see for herself the conditions which allegedly caused the deaths of more than 70 of the 350 equines used in snake antivenom production during 2000. ANIMAL PEOPLE recounted the plight of the King Institute herd in “Showdown at the Not-Okay Corral,” January/February 2001, and of Tarun in particular: “An elderly mule with long hair and overgrown hooves was down and evidently unable to rise. When ANIMAL PEOPLE pointed this out to the vet, he ordered the stable hand to make the mule rise. The stable hand pulled the mule’s tail. ANIMAL PEOPLE publisher Kim Bartlett asked him to stop, begged the vet to make him stop, and finally stopped the tail-pulling by entering the stall herself.”

Read more

Maddie’s aims to fix vet shortage

From ANIMAL PEOPLE, January/February 2001:

NAPLES, Fla.; ALAMEDA, Calif.–Hoping to hire a fulltime veterinarian, Collier County Domestic Animal Services included a state-of-the-art neutering clinic and diagnostic lab in a $3.2 million new shelter opened on January 12 in Naples, Florida. Shelter director Jodi Walters thought she had offered a competitive salary and compensation package, with the balmy climate and beaches of the Florida coast for an added attraction–but no vet applied, she told Rachelle Bott of the Naples Daily News.

Read more

New drug dart for deer

From ANIMAL PEOPLE, January/February 2001:

LONDON–Harmlessly tranquilizing or innoculating animals from many times the range of previous syringe guns, the new-design high-speed Ecodart will at last make practicable the administration of contraceptive drugs to deer, says inventor and deer management consultant Richard Price.

Conventional syringe darts land with such penetration force that they cannot be safely fired at a speed of more than 80 yards per second, Price recently told Daily Telegraph science correspondent David Derbyshire. That limits the delivery range to under 30 yards, with no crosswind–closer than deer can usually be approached.

The Ecodart flies at more than 1,500 feet per second. Made from carbon-bonded glass, the nose cone shatters on impact, releasing a gas bag which inflates to the size of a grapefruit, preventing deep penetration while propelling the drug dose into the animal.

Price unveiled the Ecodart two weeks before Humane Society of the U.S. researcher Alan Rutberg and Morris County, New Jersey, cancelled a three-year-old deer contraception study at the Frelinghuysen Arboretum. They had managed to dart only 14 deer in 1997. Just two were later relocated for examination.

A similar study underway at Irondequoit Park in Syracuse darted 65 deer, 1997-1999, but doing the job took researcher
William F. Porter and team 3,000 hours.

Showdown at the not-okay corral

From ANIMAL PEOPLE, January/February 2001:

CHENNAI, India–When lives depend on the health of horses, you keep the horses healthy. Even Wild West desperados who broke all Ten Commandments on a daily basis knew that–because the penalty for failure was to be caught and hung.

Civilization thrived in Pune and Madras, now called Chennai, for at least 5,000 years before the U.S. west was tamed.
Yet Haffkine Bio-Pharma Limited of Pune and the King Insti-tute of Preventive Medicine, in the Chennai suburb of Guindy, apparently never learned what illiterate gunslingers knew about horse care.

The two labs are now Exhibits A and B for more stringent regulation of lab animal use in India, as demanded by federal
minster for social justice and empowerment Maneka Gandhi, in a head-on clash with Tamil Nadu health minister L.K. Tripathy and Indian Medical Association state chapter president P.K. Kesavan.

Read more

How to keep mange out of shelters

From ANIMAL PEOPLE, January/February 2001:

Accompanying ANIMAL PEOPLE on shelter visits in the Chennai area was Ved Joshi, DVM, from far distant Himachal Pradesh, who rode the train for two days in each direction to discuss opportunities to take an advanced course of study in wildlife medicine in the U.S. this fall. Joshi would then return to India to teach others.

Joshi turned out to be a most valuable escort, because he knew an inexpensive way to keep mange out of animal shelters. “The insecticide Malathion can be safely used for mange control when recommended doses are employed on the animal and premises,” Joshi explained at each stop. “The product we use is Cythion, which contains 50% Malathion as its active component. The recommended dilution ratio for a dog-dipping solution or cleaning cages and floors is one part of Malathion to 1,000 parts of water, i.e., one millilitre of Malathion to each one litre of water. The
dog’s entire body is dipped in the solution until the hair and skin are wet, and the dog’s head is treated by sponging the solution over the head and face. Infections by sarcoptic and psoroptic mange mites will be cured with a single dip. Two or three dips, seven to ten days apart, should be sufficient for treatment of demodectic mange; however, while demodectic mange is not contagious, it is very hard to completely cure, and it can recur later. Collars, leashes, and bedding materials should also be dipped in the solution, to eliminate all possible sources of infection. Each newly arrived dog should be dipped before admission to the kennels to prevent reinfection outside.

“This dip will control other ecto-parasites, such as ticks and lice,” Joshi advises, “and can also be used with cattle,
buffalo, sheep, and goats.” If any animal accidentally ingests enough dip to become ill, a relatively rare occurrence, Joshi recommends administering atropine sulphate at a ratio of from 0.2 to 0.5 milligrams per kilogram of body weight. “A fourth of the dose should be given intravenously and the rest by the intramuscular route,” Joshi advises.

A shelter in India can be kept mange-free with Malathion dips and cage-and-floor-washing for as little as 50 rupees (under $1.00 U.S.) per week.

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